MCAI SOE 15th Nov 2022
PHARMACO/MEASUREMENT SOE
1. Antibiotics
Classify antibiotics
Tell me about beta lactamases
How is penicilin produced – I think I incoherently mentioned alexander fleming and some penicilinium or whatever
Where do cephalosporin act
What type of antibiotic is vancomycin
Name antibiotics acting on protein and dna synthesis
2. PD
What is agonist, partial agonist
Name examples
3. Opioid
What is opioid, opiate and narcotic
What is the mechanism of action for opioid
- explained abt pd, but they then ask what is the molecular level action of opioid
4. What are sympathomimetics
Classify them
According to adrenergic receptors
According to synthetic/natural
5. Flow
What is flow
How can flow be described (hagen pouseille)
What is difference btw laminar and turbulent flow (Reynold’s no)
How to determine if fluid is laminar or turbulent
What is density
What is unit of density
What is viscosity
What is unit of viscosity
What is bernoulli principle (pronounce bernuwi)
What is venturi effect
What is coanda effect
Name 2 anaesthetic equipment that use this principle
6. Defibrillator
What is defibrillator
What is the component of a defibrillator
What is impedance
What is thoracic impedance
PHYSIO/PHYSICS/EQUIPMENT SOE
1. How does neonates differ from adults in terms of physiology
Questions on respi, cvs, renal, cns sikit2
What is the normal blood volume for neonate
2. How dyou calculate CaO2
What about oxygen flux
There's draw action potential of pacemaker and ventricular myocyte.
And chemical changes that occur at each phase
3. What is IOP
What drug increases IOP
Intracranial Volume and relation to Pressure
What affect CPP
Cerebral autoregulation
4. HPAA
Talk about the pituitary gland anatomy and hormones it releases
How many grams does it weigh
Adrenal glands, what hormone it releases
The negative feedbacks - Explain the HPAA (specifically cortisol)
What are clinical features of Cushing’s
5. Tell me about erythropoiesis (journey from iron absorption to production from stem cells, I think?)
How is blood stored
What are the additives added for blood storage
Why is it stored in cooler temperature
Why is there less 23dpg in the blood stored
6. Artline
Draw an artline wave
Explain its component
Why is there a dicrotic notch
What info can be obtained from artline (SBP/DBP/MAP/CO/HR/rhythm/contractility/SVR)
7. Oxygen concentrator
What is it made out of
how does it concentrate oxygen
How is oxygen stored
What is this (shows a picture of nasal prong) and how does it work
Special thanks to Nazirah et. al.